Many people choose to take cannabidiol (CBD) orally, using various tinctures, capsules, and oils. It is believed that CBD may be more effective when taken regularly. Transcranial Magnetic Stimulation (TMS) is a method that helps to stimulate the brain using electromagnetic pulses. This method has very few side effects and the results can be felt in just two weeks. The greater the reported improvement in well-being after consuming CBD, the lower the Hospital Anxiety and Depression Scale (HADS) score on both subscales.
It is important to keep in mind that, in addition to CBD and other cannabinoids, there are substances from other chemical groups, such as terpenoids, flavonoids, and alkaloids. Surveys have shown that only 19% of those who took CBD consulted a doctor or pharmacist about their intake, and the majority of respondents (59%) consume CBD daily. Given the social aspect of CBD consumption, it is justified to carry out more research by interdisciplinary teams composed of psychiatrists and pharmacists. In human models, a single dose of 300 milligrams (mg) of CBD caused a marked decrease in anxiety levels after a simulated public speaking test, according to a review study. There is also the potential for dangerous drug interactions when taking CBD oil with another drug.
Research suggests that many of the side effects that occur with CBD are likely the result of drug interactions between CBD and other medications a person is taking. CBD appears to act directly on serotonin receptors, which is different from how the most commonly used antidepressants, serotonin reuptake inhibitors, work. Anyone considering using CBD should talk to a doctor about existing medications to check for interactions. A review in Frontiers in Immunology found that CBD creates a calm in the brain that is visible in scans so doctors can see how distress dissipates. Hemp-derived CBD products with less than 0.3% THC are federally legal, but are still illegal under some state laws.
When analyzing survey results, it should first be noted that only 19% of the respondents consulted their doctor or pharmacist about taking CBD. Because there have been no human studies on CBD and depression, there is no clear research to suggest the best way to use CBD for depression. Studies, including one published in Neuropsychopharmacology, have shown that CBD administered before a public speech significantly reduces general anxiety, cognitive impairment, and performance anxiety. In the world of herbal remedies, CBD is the second choice among enthusiasts. CBD oil works in a similar way for people who suffer from depression because depression occurs when serotonin levels are low.